CPI-444

  • Purchase Qty: 1
  • Unit: g(s)
  • Fob Unit Price: US $1200
  • Production Capacity:1kg
  • Payment Terms:T/T , PayPal
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Shanghai Caerulum Pharma Discovery

Business Type:Manufacturer

Country/Region:China

Ddu Verified

HOT Rank

6/10

Product Information

Description

CPI-444, also known as V81444, is an orally administered antagonist of the adenosine A2A receptor. Upon oral administration, CPI-444 binds to adenosine A2A receptors expressed on the surface of immune cells, including T-lymphocytes, natural killer (NK) cells, macrophages and dendritic cells (DCs). This prevents tumor-released adenosine from interacting with the A2A receptors on these key immune surveillance cells, thereby abrogating adenosine-induced immunosuppression in the tumor microenvironment.

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