Adavivint; SM04690- Shanghai Caerulum Pharma Discovery

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Adavivint; SM04690

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Shanghai Caerulum Pharma Discovery

Business Type:Manufacturer

Country/Region:China

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HOT Rank

8/10

Product Information

CAS:1467013-03-3
Active Ingredients:N-(5-{3-[7-(3-fluorophenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-5-yl}pyridin-3-yl)-3-methylbutanamide
Chemical Formula:C29H24FN7O
Molecular Weight:505.55
Assay:min 98%
Pharmacopeia:CP
Shelf Life:2 years
Storage:Sealed
Place of Origin:China

Description

A novel small molecule Wnt pathway inhibitor with EC50 of 3 nM in vitro; induces hMSC differentiation into mature, functional chondrocytes and decreases cartilage catabolic marker levels; significantly improves Osteoarthritis Research Society International (OARSI) histology scores and biomarkers in a rodent OA model.

Shanghai Caerulum Pharma Discovery is the manufacturer of APIs and intermediates of some of the latest compounds in the market. Our focus is on cancer, diabetes and other therapeutic areas.

Shanghai Caerulum Pharma Discovery (CPD) offers high quality and reliable chemical products and integrated biological services including:

1) Best offer for existing APIs and intermediates

2) Custom-synthesis APIs and intermediates

3) DMPK

4) Biological screening

5) Drug Safety Evaluation